Seroconversion try how many female seronegative at standard and you can seropositive during the go after-right up one of those seronegative in the baseline
Statistical methods
For the next analyses, “any HPV” describes seropositivity otherwise DNA positivity for around among the following Hours-HPV systems: sixteen, 18, 31, 33, 35, forty five, 52, and you will 58.
Any, type-specific and age-specific ( < 20,>=61 years) HR-HPV seroprevalence (at baseline and follow-up), seropersistence, seroclearance and seroconversion (at follow-up) were assessed. Seropersistence was defined as the number of women who were seropositive at baseline and follow-up among all women who were seropositive at baseline. Seroclearance was the number of women who were seropositive at baseline and seronegative at follow-up among all those seropositive at baseline.
Baseline seropositivity are weighed against concurrent cervical DNA positivity to evaluate concordance, that may only be checked-out on kind of-specific peak, given that women can be will infected with multiple version of HPV and you may the fresh new concordance reputation will likely be more for each and every type of. To get over including limit, analyses were performed at genotype height using general quoting equation (GEE) designs one to make up the possible lack of versatility anywhere between multiple observations regarding exact same woman [twenty two, 23].
Univariable and multivariable GEE models were performed to identify predictors of HR-HPV seroprevalence at baseline. Risk estimates were adjusted by potential risk factors fatos sobre mulheres IslГўndia for HPV seropositivity: age at baseline, marital status, education level, number of children, age at first sexual intercourse, lifetime number of sexual partners, high-risk sexual partner (who engaged in extra-relationship sexual activity), history of sexually transmitted disease, hormonal contraception, smoking, condom use and cervical HR-HPV DNA infection. (more…)